Karuna Therapeutics soars after $14 billion takeover by Bristol Myers

Karuna Therapeutics (KRTX) - Get Free Report shares soared Friday after the neurological-drug specialists agreed to a $14 billion takeover by pharma giant Bristol Myers Squibb (BMY) - Get Free Report. Bristol Myers said it would pay $330 a share cash for the Boston drugmaker, a 53% premium to its Thursday closing price, a deal that values the group at around $14 billion. Karuna focuses on treatments for patients suffering psychiatric and neurological conditions. Last month the Food and Drug Administration accepted its new-drug application for KarXT, a drug designed to treat schizophrenia. “Schizophrenia and Alzheimer’s disease psychosis affect millions of people worldwide, with limited to no treatment options," said Karuna's chief medical officer, Samit Hirawat. "KarXT’s novel mechanism has resulted in a transformational profile in schizophrenia, with compelling efficacy and a differentiated safety profile.” “KarXT also has the potential to deliver meaningful benefits to patients as an adjunctive treatment for patients with schizophrenia and as a first treatment for Alzheimer’s disease psychosis,” he added. Karuna Therapeutics shares were marked 47.5% higher in premarket trading immediately following news of the takeover to indicate an opening bell price of $317.50 Bristol Myers shares, meanwhile, slipped 1.6% to $59.45 each.Bristol Myers: Second major deal of '23 The deal marks the second major acquisition for Bristol Myers this year, following its $5.8 billion purchase of San Diego cancer-drug specialists Mirati Therapeutics (MRTX) - Get Free Report in October. “There are tremendous opportunities in neuroscience, and Karuna strengthens our position and accelerates the expansion and diversification of our portfolio in the space," said Bristol Myers CEO Chris Boerner. "We expect KarXT to enhance our growth through the late 2020s and into the next decade." “This transaction fits squarely within our business development priorities of pursuing assets that are strategically aligned, scientifically sound, financially attractive, and have the potential to address areas of significant unmet medical need," he added. Get investment guidance from trusted portfolio managers without the management fees. Sign up for Action Alerts PLUS now.
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*Финансовые эксперты выяснили, сколько зарабатывали родители Кевина из фильма «Один дома»*

Также есть предположение, кем они работали.
[Read more...](https://lifehacker.ru/skolko-zarabatyvali-makkalistery/)

*Подошвы кроссовок*

Фитнес, бег, командные виды спорта, паркур, занятия в зале и на улице требуют определенного типа подошвы спортивной обуви. Например, баскетбольные кроссовки для улицы имеют протектор в виде елочки , иначе игрок будет ...via forma full 5 https://ift.tt/x2XcPMn Manage Unsubscribe from these notifications or sign in to manage your Email service.IFTTT Manage on IFTTT: https://ifttt.com/myrecipes/personal/114580525
[Read more...](https://analogindex.livejournal.com/3580841.html)

*Камуфляжи армий мира*

Современные камуфляжи Германии Из всех западных стран Германия имеет наибольший опыт создания собственных камуфляжных расцветок. Собственно, первый камуфляж у немцев появился еще в Первую мировую.via forma full 5 https://ift.tt/vG0KueX Manage Unsubscribe from these notifications or sign in to manage your Email service.IFTTT Manage on IFTTT: https://ifttt.com/myrecipes/personal/114580525
[Read more...](https://analogindex.livejournal.com/3587026.html)

Подошвы кроссовок

Фитнес, бег, командные виды спорта, паркур, занятия в зале и на улице требуют определенного типа подошвы спортивной обуви. Например, баскетбольные кроссовки для улицы имеют протектор в виде елочки , иначе игрок будет ...via forma full 5 https://ift.tt/x2XcPMn Manage Unsubscribe from these notifications or sign in to manage your Email service.IFTTT Manage on IFTTT: https://ifttt.com/myrecipes/personal/114580525
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Камуфляжи армий мира

Современные камуфляжи Германии Из всех западных стран Германия имеет наибольший опыт создания собственных камуфляжных расцветок. Собственно, первый камуфляж у немцев появился еще в Первую мировую.via forma full 5 https://ift.tt/vG0KueX Manage Unsubscribe from these notifications or sign in to manage your Email service.IFTTT Manage on IFTTT: https://ifttt.com/myrecipes/personal/114580525
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*what the fuck is going down on twitch*

submitted by /u/mythril- to r/shitposting [link] [comments]
[Read more...](https://www.reddit.com/r/shitposting/comments/18oavqz/what_the_fuck_is_going_down_on_twitch/)

what the fuck is going down on twitch

submitted by /u/mythril- to r/shitposting link comments
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*Dear fucking god*

submitted by /u/infinitysaga to r/Gamingcirclejerk [link] [comments]
[Read more...](https://www.reddit.com/r/Gamingcirclejerk/comments/18obeg7/dear_fucking_god/)

*Stock Market Today: Stocks mixed as inflation cools; Nike drags Dow on muted outlook*

Check back for updates throughout the trading day U.S. equity futures traded mixed Friday but remain on track for a positive five-day stretch that would extend the S&P 500's weekly winning streak to eight, the best since 2017, heading into the final trading sessions of the year. Core inflation is now just below 2% on a six-month average basis. Shutterstock Updated at 8:55 AM EST Inflation on target? The Fed's favored inflation gauge is now trending at the central bank's preferred 2% target, based on data compiled over the past six months, cementing the case for spring rate cuts. Futures were modestly firmer following the data release with futures tied to the S&P 500 indicating a 10 point opening bell gain and those linked to the Dow suggesting a 52 point decline. The Nasdaq is called 37 points higher. Benchmark 10-year Treasury note yields were 2 basis points higher at 4.871% thanks in part to modestly firmer personal income gains found in the release. Two-year notes were pegged at 4.344%.Related: Fed Inflation gauge falls below 3%, with core prices at March 2021 low Updated at 8:00 AM EST Big drug deal Bristol Myers added to its recent string of major acquisitions with the $14 billion takeover of neurological drug specialists Karuna Therapeutics, sending shares in the Boston-based group soaring 47% in pre-market trading.Related: Karuna Therapeutics soars after $14 billion takeover by Bristol Myers Stock Market Today The major U.S. stock markets are expected to remain open for the full trading day Friday, although bond markets will close shop at around 1 pm eastern time ahead of the three-day holiday weekend. Traders will first have to navigate a key inflation reading at 8:30 am, when the Bureau of Economic Analysis publishes its closely watched Personal Consumption Expenditures Price Index for November. Economists expect the Federal Reserve's preferred inflation gauge to show another notable slowing in overall and core price pressures heading into December that are likely to cement the market's case for rate cuts beginning in the spring, Stocks, meanwhile, are likely to be pulled lower by Nike's (NKE) - Get Free Report disappointing fiscal-second-quarter earnings and muted near-term outlook. That's clipped consumer and sports apparel stocks and looks to set to take around 92 points from the Dow at the start of trading.Related: Nike slumps after cutting full-year sales forecast on sportswear weakness Futures contracts tied to the S&P 500 are indicating a 1 point opening bell gain, with the Dow called 77 points lower and the Nasdaq set for a 12 point decline. In overseas markets, the Stoxx 600 was marked 0.1% higher in early Frankfurt trading and was holding on to a 12% gain for the year. The FTSE 100 rose 0.13% in London. Overnight in Asia, a newly announced crackdown on the videogame industry by officials in Beijing hammered gaming and tech stocks and pulled the regionwide MSCI ex-Japan index 0.28% lower into the close of trading. Japan's Nikkei 225, meanwhile, rose 0.1% in muted Friday trading to take its 2023 gain to just under 29%. Action Alerts PLUS offers expert portfolio guidance to help you make informed investing decisions. Sign up now.
[Read more...](https://www.thestreet.com/investing/stocks/stock-market-today-stocks-slip-with-inflation-data-in-focus-nike-tumbles)

Dear fucking god

submitted by /u/infinitysaga to r/Gamingcirclejerk link comments
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Stock Market Today: Stocks mixed as inflation cools; Nike drags Dow on muted outlook

Check back for updates throughout the trading day U.S. equity futures traded mixed Friday but remain on track for a positive five-day stretch that would extend the S&P 500's weekly winning streak to eight, the best since 2017, heading into the final trading sessions of the year. Core inflation is now just below 2% on a six-month average basis. Shutterstock Updated at 8:55 AM EST Inflation on target? The Fed's favored inflation gauge is now trending at the central bank's preferred 2% target, based on data compiled over the past six months, cementing the case for spring rate cuts. Futures were modestly firmer following the data release with futures tied to the S&P 500 indicating a 10 point opening bell gain and those linked to the Dow suggesting a 52 point decline. The Nasdaq is called 37 points higher. Benchmark 10-year Treasury note yields were 2 basis points higher at 4.871% thanks in part to modestly firmer personal income gains found in the release. Two-year notes were pegged at 4.344%.Related: Fed Inflation gauge falls below 3%, with core prices at March 2021 low Updated at 8:00 AM EST Big drug deal Bristol Myers added to its recent string of major acquisitions with the $14 billion takeover of neurological drug specialists Karuna Therapeutics, sending shares in the Boston-based group soaring 47% in pre-market trading.Related: Karuna Therapeutics soars after $14 billion takeover by Bristol Myers Stock Market Today The major U.S. stock markets are expected to remain open for the full trading day Friday, although bond markets will close shop at around 1 pm eastern time ahead of the three-day holiday weekend. Traders will first have to navigate a key inflation reading at 8:30 am, when the Bureau of Economic Analysis publishes its closely watched Personal Consumption Expenditures Price Index for November. Economists expect the Federal Reserve's preferred inflation gauge to show another notable slowing in overall and core price pressures heading into December that are likely to cement the market's case for rate cuts beginning in the spring, Stocks, meanwhile, are likely to be pulled lower by Nike's (NKE) - Get Free Report disappointing fiscal-second-quarter earnings and muted near-term outlook. That's clipped consumer and sports apparel stocks and looks to set to take around 92 points from the Dow at the start of trading.Related: Nike slumps after cutting full-year sales forecast on sportswear weakness Futures contracts tied to the S&P 500 are indicating a 1 point opening bell gain, with the Dow called 77 points lower and the Nasdaq set for a 12 point decline. In overseas markets, the Stoxx 600 was marked 0.1% higher in early Frankfurt trading and was holding on to a 12% gain for the year. The FTSE 100 rose 0.13% in London. Overnight in Asia, a newly announced crackdown on the videogame industry by officials in Beijing hammered gaming and tech stocks and pulled the regionwide MSCI ex-Japan index 0.28% lower into the close of trading. Japan's Nikkei 225, meanwhile, rose 0.1% in muted Friday trading to take its 2023 gain to just under 29%. Action Alerts PLUS offers expert portfolio guidance to help you make informed investing decisions. Sign up now.
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*5 фактов о фастфуде, которые вряд ли известны даже его фанатам*

Откуда на самом деле берутся полоски от гриля на котлетах, что такое аромамаркетинг и сколько можно прожить на одних бургерах.
[Read more...](https://lifehacker.ru/fakty-o-fastfude/)

*Правильное*

Погоны представляют собой часть одежды военнослужащего, а расположение звезд на погонах принято считать знаком отличия по званию между сослуживцами. Однако очень важно знать, на каком расстоянии должны находиться ...via forma full 5 https://ift.tt/Cq2Ad3p Manage Unsubscribe from these notifications or sign in to manage your Email service.IFTTT Manage on IFTTT: https://ifttt.com/myrecipes/personal/114580525
[Read more...](https://analogindex.livejournal.com/3583875.html)

*Форменная одежда*

Форменная одежда для руководства, иных должностных лиц центрального аппарата и ...via forma full 5 https://ift.tt/J2wkM8g Manage Unsubscribe from these notifications or sign in to manage your Email service.IFTTT Manage on IFTTT: https://ifttt.com/myrecipes/personal/114580525
[Read more...](https://analogindex.livejournal.com/3584152.html)

Правильное

Погоны представляют собой часть одежды военнослужащего, а расположение звезд на погонах принято считать знаком отличия по званию между сослуживцами. Однако очень важно знать, на каком расстоянии должны находиться ...via forma full 5 https://ift.tt/Cq2Ad3p Manage Unsubscribe from these notifications or sign in to manage your Email service.IFTTT Manage on IFTTT: https://ifttt.com/myrecipes/personal/114580525
Read more...

Форменная одежда

Форменная одежда для руководства, иных должностных лиц центрального аппарата и ...via forma full 5 https://ift.tt/J2wkM8g Manage Unsubscribe from these notifications or sign in to manage your Email service.IFTTT Manage on IFTTT: https://ifttt.com/myrecipes/personal/114580525
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*Surprise, Surprise: This Is the U.S. State Everyone Moved to This Year*

Hint: It’s not California. READ MORE...
[Read more...](https://www.apartmenttherapy.com/most-popular-us-state-to-move-to-2023-37358437?utm_source=RSS&utm_medium=feed&utm_campaign=Category%2FChannel%3A+main)

*Movies you adored as a teen but find extra cringy to watch as an adult?*

Like the title says. Just had this thought. There are movies you watch as a teen and are certain are masterpieces, like it's so original and well executed and resonates so much with you. Then you grow up, try rewatching as an adult, and you just can't stand the cringe that emanates from it, and you can't comprehend why you loved it so much! I wondered what were some of those for other people. I enjoy watching cringe from time to time. For me I'd say Eragon and Equilibrium. The 1st one I was just so happy that they made a movie, I was in awe to just SEE this universe! But rewatching it in my 20s, I realized I was just in love with the idea. The 2nd is a guilty pleasure. It fit so well with my rebel/broody phase as a teen, I actually thought the movie was groundbreaking. Well... I still enjoy watching it, but it's just nostalgia now. I suffer through it xD submitted by /u/Constant_Bake5501 to r/movies [link] [comments]
[Read more...](https://www.reddit.com/r/movies/comments/18o2dp3/movies_you_adored_as_a_teen_but_find_extra_cringy/)

Movies you adored as a teen but find extra cringy to watch as an adult?

Like the title says. Just had this thought. There are movies you watch as a teen and are certain are masterpieces, like it's so original and well executed and resonates so much with you. Then you grow up, try rewatching as an adult, and you just can't stand the cringe that emanates from it, and you can't comprehend why you loved it so much! I wondered what were some of those for other people. I enjoy watching cringe from time to time. For me I'd say Eragon and Equilibrium. The 1st one I was just so happy that they made a movie, I was in awe to just SEE this universe! But rewatching it in my 20s, I realized I was just in love with the idea. The 2nd is a guilty pleasure. It fit so well with my rebel/broody phase as a teen, I actually thought the movie was groundbreaking. Well... I still enjoy watching it, but it's just nostalgia now. I suffer through it xD submitted by /u/ConstantBake5501 to r/movies [link] [comments]
[Read more...](https://www.reddit.com/r/movies/comments/18o2dp3/moviesyouadoredasateenbutfindextracringy/)